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Overview
Thymosin Alpha 1 (TA1) is a naturally occurring thymic peptide widely investigated for its immunomodulatory properties, making it a key research compound for studies in immune system regulation.
Product Description
Thymosin Alpha 1 (TA1), also known as Thymalfasin, is a synthetic version of a naturally occurring peptide originally isolated from the thymus gland. This 28-amino acid peptide plays a crucial role in the maturation, differentiation, and function of T-cells, which are central to adaptive immunity. Research applications for Thymosin Alpha 1 are extensive, primarily focusing on its capacity to enhance immune responses, modulate cytokine production, and support immune system balance. Studies often explore its potential in areas such as infectious disease models, oncology research, and investigations into autoimmune conditions, where immune system dysregulation is a significant factor. Its mechanism of action involves stimulating the differentiation of T-lymphocyte precursors, promoting the production of various cytokines (e.g., interferons, interleukins), and enhancing the activity of natural killer cells and dendritic cells.
For optimal research integrity and compound stability, Thymosin Alpha 1 should be handled with care. It is typically supplied as a lyophilized powder and should be reconstituted using sterile, bacteriostatic water or a suitable solvent as per specific experimental protocols. Avoid repeated freeze-thaw cycles, as this can degrade the peptide's activity. Researchers should always use aseptic techniques during handling to prevent contamination, which could compromise experimental results. Personal protective equipment, including gloves and eye protection, is recommended during preparation and use.
Proper storage is critical to maintain the potency and shelf-life of Thymosin Alpha 1. The lyophilized powder should be stored long-term at -20°C or below, away from light and moisture. Once reconstituted, solutions should be stored at 2-8°C and used within a short period, typically 24-72 hours, depending on the solvent and concentration. For longer-term storage of reconstituted solutions, aliquoting and freezing at -20°C or below may be considered, though repeated freezing and thawing should still be avoided. Always refer to the specific product's Certificate of Analysis and manufacturer guidelines for the most precise storage and handling recommendations.
Certificates of Analysis
Research Use Only
This product is intended for research and laboratory use only. Not for human consumption. By purchasing this product, you confirm that you are a qualified researcher and will use this compound in accordance with all applicable laws and regulations.
