SS-31 10mg

SS-31, also known as Elamipretide, is a fascinating and highly selective tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2) designed to specifically localize to the inner mitochondrial membrane. Its unique structure allows it to penetrate cell membranes efficiently and bind to cardiolipin, a phospholipid crucial for mitochondrial function. This interaction is believed to stabilize the inner mitochondrial membrane, preserve mitochondrial cristae structure, and enhance electron transport chain activity. Research applications for SS-31 primarily focus on its role in mitigating mitochondrial dysfunction and oxidative stress. Studies investigate its potential therapeutic effects in models of ischemia-reperfusion injury, neurodegenerative diseases (e.g., Parkinson's, Alzheimer's), cardiovascular disorders, kidney disease, and aging-related conditions. Researchers utilize SS-31 to explore mechanisms of mitochondrial protection, bioenergetic improvement, and reduction of reactive oxygen species (ROS) production, making it a valuable tool in mitochondrial biology and drug discovery. For optimal research integrity, SS-31 should be handled with care, preferably in a controlled laboratory environment. It is recommended to store SS-31 at -20°C or below, protected from light and moisture, to maintain its stability and purity. Prior to use, allow the vial to reach room temperature and reconstitute as per specific experimental protocols, typically with sterile water or a suitable buffer. Avoid repeated freeze-thaw cycles to preserve its structural integrity and biological activity.